Acute Disseminated Encephalomyelitis: Current Understanding and Controversies
نویسندگان
چکیده
منابع مشابه
Acute disseminated encephalomyelitis: current understanding and controversies.
Acute disseminated encephalomyelitis (ADEM) is an uncommon monophasic idiopathic inflammatory demyelinating disease. Available diagnostic criteria do not reliably distinguish it from first presentations of relapsing diseases such as multiple sclerosis (MS) and neuromyelitis optica (NMO). In this article, we review current concepts about ADEM and what distinguishes it from other idiopathic infla...
متن کاملAcute Disseminated Encephalomyelitis in Childhood; Epidemiologic, Clinical, and Laboratory Features
Background: Acute disseminated encephalomyelitis (ADEM), which occurs spontaneously or after systemic viral infection and vaccination mostly affects children. This study aims at describing the epidemiologic, clinical, neuroimaging, laboratory features, treatment and outcome in children who diagnosed as having ADEM and admitted in a referral center in Tehran. Methods: This descriptive prospectiv...
متن کاملAcute disseminated encephalomyelitis.
Acute disseminated encephalomyelitis (ADEM) is a monophasic inflammatory disorder of the central nervous system (CNS). Unlike viral encephalitis, microorganisms do not invade the CNS. Instead, ADEM is a postinfectious disease mediated by auto-reactive cells or molecules. Clinical characteristics of ADEM are consistent with disseminated involvement of the CNS, including encephalopathy and pyrami...
متن کاملAcute disseminated encephalomyelitis
Acute disseminated encephalomyelitis (ADEM) is an acute demyelinating disorder of the central nervous system, and is characterised by multifocal white matter involvement. Diffuse neurological signs along with multifocal lesions in brain and spinal cord characterise the disease. Possibly, a T cell mediated autoimmune response to myelin basic protein, triggered by an infection or vaccination, und...
متن کاملAcute disseminated encephalomyelitis.
The advent of magnetic resonance imaging (MRI) has contributed to increase the interest and awareness in childhood white matter disorders. Pediatric inflammatory demyelinating diseases of the central nervous system (CNS) are clinically heterogeneous with respect to their mode of presentation, clinical severity, rate of progression, and prognosis. Acute disseminated encephalomyelitis (ADEM) is a...
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ژورنال
عنوان ژورنال: Seminars in Neurology
سال: 2008
ISSN: 0271-8235,1098-9021
DOI: 10.1055/s-2007-1019130